Hypothalamo-Hypophyseal System

**Definition:** A collection of NEURONS, tracts of NERVE FIBERS, endocrine tissue, and blood vessels in the HYPOTHALAMUS and the PITUITARY GLAND. This hypothalamo-hypophyseal portal circulation provides the mechanism for hypothalamic neuroendocrine (HYPOTHALAMIC HORMONES) regulation of pituitary function and the release of various PITUITARY HORMONES into the systemic circulation to maintain HOMEOSTASIS.

**Tree numbers:** - A06.688.357 - A08.186.211.180.497.352.435 - A08.186.211.200.317.357.352.435 - A08.713.357

**Synonyms:** - Hypophyseal Portal System - Hypothalamic Hypophyseal System - Hypothalamic-Pituitary Unit