Immunoglobulin Idiotypes

**Definition:** Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.

**Tree numbers:** - D12.644.541.500.745 - D12.776.124.486.485.680.745 - D12.776.124.790.651.680.745 - D12.776.377.715.548.680.745 - D23.050.550.750 - G02.111.570.060.425.580 - G12.500.450

**Synonyms:** - Ig Idiotypes - Idiotypes, Immunoglobulin