Immunologic Capping

**Definition:** An energy dependent process following the crosslinking of B CELL ANTIGEN RECEPTORS by multivalent ligands (bivalent anti-antibodies, LECTINS or ANTIGENS), on the B-cell surface. The crosslinked ligand-antigen receptor complexes collect in patches which flow to and aggregate at one pole of the cell to form a large mass - the cap. The caps may then be endocytosed or shed into the environment.

**Tree numbers:** - G04.774.612 - G12.122.612

**Synonyms:** - Capping, Immunologic - Immunological Capping