Insulin-Like Growth Factor I

**Definition:** A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.

**Tree numbers:** - D12.644.276.742.500.001 - D12.776.124.862.001 - D23.529.742.500.001

**Synonyms:** - IGF-1 - IGF-I - IGF-I-SmC - Insulin Like Growth Factor I - Insulin-Like Somatomedin Peptide I - Somatomedin C