Interleukin-1

**Definition:** A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation.

**Tree numbers:** - D12.644.276.374.465.010 - D12.644.276.374.500.400 - D12.776.467.374.465.010 - D12.776.467.374.500.400 - D23.529.374.465.131 - D23.529.374.500.400

**Synonyms:** - Epidermal Cell Derived Thymocyte-Activating Factor - IL-1 - Interleukin I - Lymphocyte-Activating Factor - Macrophage Cell Factor - T Helper Factor