D007645Level 5
Keratoderma, Palmoplantar
**Definition:** Group of mostly hereditary disorders characterized by thickening of the palms and soles as a result of excessive keratin formation leading to hypertrophy of the stratum corneum (hyperkeratosis).
**Tree numbers:** - C16.320.850.475 - C17.800.428.435 - C17.800.827.475
**Synonyms:** - Hyperkeratosis Palmaris et Plantaris - Keratosis Palmaris et Plantaris - Keratosis, Palmoplantar - Palmoplantar Keratoderma
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