Peptidyl-Dipeptidase A

**Definition:** A peptidyl-dipeptidase that catalyzes the release of a C-terminal dipeptide, oligopeptide--Xaa-Yaa, when Xaa is not Pro, and Yaa is neither Asp nor Glu. Thus, conversion of ANGIOTENSIN I to ANGIOTENSIN II, with increase in vasoconstrictor activity, but no action on angiotensin II. It is also able to inactivate BRADYKININ, a potent vasodilator; and has a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. (From https://www.uniprot.org April 15, 2020).

**Tree numbers:** - D08.811.277.656.350.350.687

**Synonyms:** - Peptidase P - ACE1 Protein - Antigens, CD143 - Angiotensin Converting Enzyme - Angiotensin I-Converting Enzyme - Carboxycathepsin - Kininase A - Kininase II - Dipeptidyl Peptidase A - CD143 Antigens - ACE1 Angiotensin-Converting Enzyme 1 - Dipeptidyl Carboxypeptidase I - Angiotensin Converting Enzyme 1