Phosphatidylcholine-Sterol O-Acyltransferase

**Definition:** An enzyme secreted from the liver into the plasma of many mammalian species. It catalyzes the esterification of the hydroxyl group of lipoprotein cholesterol by the transfer of a fatty acid from the C-2 position of lecithin. In familial lecithin:cholesterol acyltransferase deficiency disease, the absence of the enzyme results in an excess of unesterified cholesterol in plasma.

**Tree numbers:** - D08.811.913.050.625

**Synonyms:** - Lecithin Acyltransferase - Cholesterol Ester Lysolecithin Acyltransferase - Lecithin Cholesterol Acyltransferase - Phosophatidylcholine-Sterol Acyltransferase