Metformin

**Definition:** A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)

**Tree numbers:** - D02.078.370.141.450

**Synonyms:** - Dimethylbiguanidine - Dimethylguanylguanidine