Methylmalonyl-CoA Mutase

**Definition:** An enzyme that catalyzes the conversion of methylmalonyl-CoA to succinyl-CoA by transfer of the carbonyl group. It requires a cobamide coenzyme. A block in this enzymatic conversion leads to the metabolic disease, methylmalonic aciduria. EC 5.4.99.2.

**Tree numbers:** - D08.811.399.520.625

**Synonyms:** - Methylmalonyl-CoA Isomerase