D008926Level 9
Plicamycin
**Definition:** A tricyclic pentaglycosidic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA. It is used as a fluorescent dye and as an antineoplastic agent, especially in bone and testicular tumors. Plicamycin is also used to reduce hypercalcemia, especially that due to malignancies.
**Tree numbers:** - D02.455.426.559.847.562.050.650 - D04.615.562.050.650 - D09.408.051.059.650
**Synonyms:** - Aureolic Acid - Mithramycin - Mitramycin
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