Myosin-Light-Chain Kinase

**Definition:** An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain phosphate and ADP, and requires calcium and CALMODULIN. The 20-kDa light chain is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors. The enzyme plays a central role in the regulation of smooth muscle contraction.

**Tree numbers:** - D08.811.913.696.620.682.700.125.500 - D12.776.476.563.125.500

**Synonyms:** - Myosin LCK - Myosin Kinase - Myosin Regulatory Light-Chain Kinase