Neuronal Ceroid-Lipofuscinoses

**Definition:** A group of severe neurodegenerative diseases characterized by intracellular accumulation of autofluorescent wax-like lipid materials (CEROID; LIPOFUSCIN) in neurons. There are several subtypes based on mutations of the various genes, time of disease onset, and severity of the neurological defects such as progressive DEMENTIA; SEIZURES; and visual failure.

**Tree numbers:** - C10.574.500.550 - C16.320.400.600 - C16.320.565.398.641.509 - C18.452.584.563.641.509 - C18.452.648.398.641.509

**Synonyms:** - Ceroid-Lipofuscinosis, Neuronal - Lipofuscinosis, Neuronal Ceroid - Neuronal Ceroid Lipofuscinosis - Ceroid Storage Disease - Lipofuscin Storage Disease - Neuronal Ceroid-Lipofuscinosis