Novobiocin

**Definition:** An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189)

**Tree numbers:** - D03.383.663.283.446.139.500 - D03.633.100.150.446.139.500 - D09.408.554

**Synonyms:** - Crystallinic Acid - Streptonivicin