Osteogenesis Imperfecta

**Definition:** COLLAGEN DISEASES characterized by brittle, osteoporotic, and easily fractured bones. It may also present with blue sclerae, loose joints, and imperfect dentin formation. Most types are autosomal dominant and are associated with mutations in COLLAGEN TYPE I.

**Tree numbers:** - C05.116.099.708.685 - C16.320.737 - C17.300.200.540

**Synonyms:** - Fragilitas Ossium - Brittle Bone Disease