Peptide Chain Initiation, Translational

**Definition:** A process of GENETIC TRANSLATION whereby the formation of a peptide chain is started. It includes assembly of the RIBOSOME components, the MESSENGER RNA coding for the polypeptide to be made, INITIATOR TRNA, and PEPTIDE INITIATION FACTORS; and placement of the first amino acid in the peptide chain. The details and components of this process are unique for prokaryotic protein biosynthesis and eukaryotic protein biosynthesis.

**Tree numbers:** - G02.111.660.871.650 - G03.734.871.650

**Synonyms:** - Translational Peptide Chain Initiation - Chain Initiation, Peptide, Translational - Protein Chain Initiation, Translational - Translational Initiation, Protein - Translation Initiation, Protein - Protein Biosynthesis Initiation - Translation Initiation, Genetic - Protein Translation Initiation