Tissue Plasminogen Activator

**Definition:** A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.

**Tree numbers:** - D08.811.277.656.300.760.875 - D08.811.277.656.959.350.875 - D12.776.124.125.662.768 - D23.119.970

**Synonyms:** - Tissue Activator D-44 - Plasminogen Activator, Tissue-Type - Tissue-Type Plasminogen Activator - TTPA - T-Plasminogen Activator - Alteplase - Tisokinase