Polymyxin B

**Definition:** A mixture of polymyxins B1 and B2, obtained from BACILLUS POLYMYXA strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for treatment of infections with gram-negative bacteria, but may be neurotoxic and nephrotoxic.

**Tree numbers:** - D04.345.566.780.750 - D10.477.750.750 - D12.644.050.600.750 - D12.644.066.500.600.750 - D12.644.641.780.750 - D12.776.543.695.054.600.750