Adenomatous Polyposis Coli

**Definition:** A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.

**Tree numbers:** - C04.557.470.035.215.100 - C04.588.274.476.411.307.089 - C04.700.100 - C06.301.371.411.307.090 - C06.405.249.411.307.090 - C06.405.469.158.356.090 - C06.405.469.491.307.090 - C06.405.469.578.249 - C16.320.700.100

**Synonyms:** - Polyposis Coli, Familial - Polyposis Syndrome, Familial - Familial Adenomatous Polyposis Coli - Adenomatous Polyposis Coli, Familial - Adenomatous Polyposis of the Colon - Familial Adenomatous Polyposis - Familial Polyposis Coli - Familial Adenomatous Polyposis of the Colon - Familial Multiple Polyposi - Familial Polyposis of the Colon - Familial Multiple Polyposis - Familial Multiple Polyposis Syndrome - Familial Polyposis Syndrome - Myh-Associated Polyposis - Hereditary Polyposis Coli - Polyposis Coli