Prothrombin

**Definition:** A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia.

**Tree numbers:** - D08.622.709 - D12.776.124.125.800 - D12.776.811.243.709 - D23.119.945

**Synonyms:** - Coagulation Factor II - Factor II - Differentiation Reversal Factor - Blood Coagulation Factor II