Pulmonary Alveolar Proteinosis

**Definition:** A PULMONARY ALVEOLI-filling disease, characterized by dense phospholipoproteinaceous deposits in the alveoli, cough, and DYSPNEA. This disease is often related to, congenital or acquired, impaired processing of PULMONARY SURFACTANTS by alveolar macrophages, a process dependent on GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR.

**Tree numbers:** - C08.381.719

**Synonyms:** - Alveolar Proteinoses, Pulmonary - Alveolar Proteinosis, Pulmonary - Proteinoses, Pulmonary Alveolar - Proteinosis, Pulmonary Alveolar - Pulmonary Alveolar Proteinoses