Pyrimidine Dimers

**Definition:** Dimers found in DNA chains damaged by ULTRAVIOLET RAYS. They consist of two adjacent PYRIMIDINE NUCLEOTIDES, usually THYMINE nucleotides, in which the pyrimidine residues are covalently joined by a cyclobutane ring. These dimers block DNA REPLICATION.

**Tree numbers:** - D03.383.742.686.600 - D13.695.578.424.600 - D13.695.740.600 - G05.200.615

**Synonyms:** - Cyclobutane Pyrimidine Dimer - Cyclobutane-Pyrimidine Dimers - Pyrimidine Dimer - Cyclobutane-Pyrimidine Dimer