Pyroglutamyl-Peptidase I

**Definition:** An enzyme that catalyzes the release of a N-terminal pyroglutamyl group from a polypeptide provided the next residue is not proline. It is inhibited by thiol-blocking reagents and occurs in mammalian tissues, microorganisms, and plants. (From Enzyme Nomenclature, 1992) EC 3.4.19.3.

**Tree numbers:** - D08.811.277.656.350.100.755

**Synonyms:** - 5-Oxoprolyl-Peptidase - Pyroglutamate Aminopeptidase - Pyroglutamyl-Peptide Hydrolase - Pyrrolidonecarboxylate Peptidase - Pyrrolidonyl Peptidase