Receptors, Histamine H1

**Definition:** A class of histamine receptors discriminated by their pharmacology and mode of action. Most histamine H1 receptors operate through the inositol phosphate/diacylglycerol second messenger system. Among the many responses mediated by these receptors are smooth muscle contraction, increased vascular permeability, hormone release, and cerebral glyconeogenesis. (From Biochem Soc Trans 1992 Feb;20(1):122-5)

**Tree numbers:** - D12.776.543.750.670.450.300 - D12.776.543.750.695.350 - D12.776.543.750.720.480.300

**Synonyms:** - H1 Receptor - H1 Receptors - Receptors, H1 - Histamine H1 Receptor - Histamine H1 Receptors