Chronic Kidney Disease-Mineral and Bone Disorder

**Definition:** Decalcification of bone or abnormal bone development due to chronic KIDNEY DISEASES, in which 1,25-DIHYDROXYVITAMIN D3 synthesis by the kidneys is impaired, leading to reduced negative feedback on PARATHYROID HORMONE. The resulting SECONDARY HYPERPARATHYROIDISM eventually leads to bone disorders.

**Tree numbers:** - C05.116.198.816.750 - C12.050.351.968.419.795 - C12.200.777.419.080 - C12.950.419.795 - C18.452.104.816.750 - C18.452.174.845.750 - C18.654.521.500.133.770.734.750 - C19.642.355.480.500 - C23.550.291.500.290

**Synonyms:** - CKD-MBD