D012202Level 5
Reye Syndrome
**Definition:** A form of encephalopathy with fatty infiltration of the LIVER, characterized by brain EDEMA and VOMITING that may rapidly progress to SEIZURES; COMA; and DEATH. It is caused by a generalized loss of mitochondrial function leading to disturbances in fatty acid and CARNITINE metabolism.
**Tree numbers:** - C06.552.241.649 - C10.228.140.163.780 - C18.452.132.780
**Synonyms:** - Fatty Liver with Encephalopathy - Reye's Syndrome - Reye-Johnson Syndrome
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