Rh Isoimmunization

**Definition:** The process by which fetal Rh+ erythrocytes enter the circulation of an Rh- mother, causing her to produce IMMUNOGLOBULIN G antibodies, which can cross the placenta and destroy the erythrocytes of Rh+ fetuses. Rh isoimmunization can also be caused by BLOOD TRANSFUSION with mismatched blood.

**Tree numbers:** - G09.188.114.750 - G12.122.780 - G12.186.750

**Synonyms:** - Isoimmunization, Rhesus