Rosette Formation

**Definition:** The in vitro formation of clusters consisting of a cell (usually a lymphocyte) surrounded by antigenic cells or antigen-bearing particles (usually erythrocytes, which may or may not be coated with antibody or antibody and complement). The rosette-forming cell may be an antibody-forming cell, a memory cell, a T-cell, a cell bearing surface cytophilic antibodies, or a monocyte possessing Fc receptors. Rosette formation can be used to identify specific populations of these cells.

**Tree numbers:** - E01.370.225.812.706 - E05.200.812.706 - E05.478.594.730

**Synonyms:** - Immunocytoadherence