Saccharopine Dehydrogenases

**Definition:** Amine oxidoreductases that use either NAD+ (EC 1.5.1.7) or NADP+ (EC 1.5.1.8) as an acceptor to form L-LYSINE or NAD+ (EC 1.5.1.9) or NADP+ (EC 1.5.1.10) as an acceptor to form L-GLUTAMATE. Deficiency of this enzyme causes HYPERLYSINEMIAS.

**Tree numbers:** - D08.811.682.662.750

**Synonyms:** - Saccharopine Dehydrogenase - Lysine-Ketoglutarate Reductase