Smallpox Vaccine

**Definition:** A VACCINIA VIRUS vaccine used for immunization against SMALLPOX. It is now recommended only for laboratory workers exposed to SMALLPOX VIRUS. Certain countries continue to vaccinate those in the military service. Rare complications most often associated with older generation smallpox vaccines include VACCINIA, secondary bacterial infections, and ENCEPHALOMYELITIS. Because MONKEYPOX VIRUS and SMALLPOX VIRUS are both ORTHOPOXVIRUS and are closely related smallpox vaccines provide effective CROSS-PROTECTION against MPOX, MONKEYPOX (https://www.cdc.gov/poxvirus/monkeypox/clinicians/smallpox-vaccine.html).

**Tree numbers:** - D20.215.894.899.859

**Synonyms:** - Small Pox Vaccine