Suramin

**Definition:** A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.

**Tree numbers:** - D02.455.426.559.847.638.555.750 - D02.886.645.600.080.050.650.750 - D04.615.638.555.750