Threonine Dehydratase

**Definition:** A pyridoxal-phosphate protein that catalyzes the deamination of THREONINE to 2-ketobutyrate and AMMONIA. The role of this enzyme can be biosynthetic or biodegradative. In the former role it supplies 2-ketobutyrate required for ISOLEUCINE biosynthesis, while in the latter it is only involved in the breakdown of threonine to supply energy. This enzyme was formerly listed as EC 4.2.1.16.

**Tree numbers:** - D08.811.520.232.400.850

**Synonyms:** - Threonine Ammonia-Lyase - Threonine Deaminase - Threonine Dehydrase