Tretinoin

**Definition:** An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).

**Tree numbers:** - D02.455.326.271.665.202.495.818.500 - D02.455.426.392.368.367.379.249.700.860.500 - D02.455.849.131.495.818.800 - D02.455.849.291.925.500 - D23.767.261.700.780

**Synonyms:** - all-trans-Retinoic Acid - Retinoic Acid - trans-Retinoic Acid - Vitamin A Acid