Vitamin D-Binding Protein

**Definition:** An alpha-globulin found in the plasma of man and other vertebrates. It is apparently synthesized in the liver and carries vitamin D and its metabolites through the circulation and mediates the response of tissue. It is also known as group-specific component (Gc). Gc subtypes are used to determine specific phenotypes and gene frequencies. These data are employed in the classification of population groups, paternity investigations, and in forensic medicine.

**Tree numbers:** - D12.776.157.920

**Synonyms:** - 25-HCC-Binding Protein - 25-Hydroxycholecalciferol-Binding Protein - 25-Hydroxyvitamin D-Binding Protein - Calciferol-Binding Protein - Gc Globulin - Group-Specific Component Globulin - Transcalciferin - Vitamin D-Binding Globulin