2-Acetylaminofluorene

**Definition:** A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.

**Tree numbers:** - D02.065.064.150 - D02.241.081.018.110.080 - D02.455.426.559.847.389.050 - D04.615.389.050

**Synonyms:** - 2-Acetamidofluorene - 2-Fluorenylacetamide - Fluoren-2-ylacetamide - 2-AAF - N-Acetyl-2-Aminofluorene - AAF, Aminofluorene - N-2-Fluorenylacetamide