D015093Level 7
Meglutol
**Definition:** An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.
**Tree numbers:** - D02.241.081.337.351.550
**Synonyms:** - 3-Hydroxy-3-methylglutaric Acid - 3-Hydroxy-3-methylpentanedioic Acid - beta-Hydroxy-beta-Methylglutarate
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