Transforming Growth Factors

**Definition:** Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA.

**Tree numbers:** - D12.644.276.963 - D12.776.467.960 - D23.529.960

**Synonyms:** - Transforming Growth Factor