Hereditary Sensory and Motor Neuropathy

**Definition:** A group of slowly progressive inherited disorders affecting motor and sensory peripheral nerves. Subtypes include HMSNs I-VII. HMSN I and II both refer to CHARCOT-MARIE-TOOTH DISEASE. HMSN III refers to hypertrophic neuropathy of infancy. HMSN IV refers to REFSUM DISEASE. HMSN V refers to a condition marked by a hereditary motor and sensory neuropathy associated with spastic paraplegia (see SPASTIC PARAPLEGIA, HEREDITARY). HMSN VI refers to HMSN associated with an inherited optic atrophy (OPTIC ATROPHIES, HEREDITARY), and HMSN VII refers to HMSN associated with retinitis pigmentosa. (From Adams et al., Principles of Neurology, 6th ed, p1343)

**Tree numbers:** - C10.500.300 - C10.574.500.495 - C10.668.829.800.300 - C16.131.666.300 - C16.320.400.375

**Synonyms:** - Herditary Sensory and Motor Neuropathy - Hereditary Motor and Sensory Neuropathies - Hereditary Motor and Sensory Neuropathy - HMSN - Neuropathies, Hereditary Motor and Sensory