Glomerulonephritis, Membranoproliferative

**Definition:** Chronic glomerulonephritis characterized histologically by proliferation of MESANGIAL CELLS, increase in the MESANGIAL EXTRACELLULAR MATRIX, and a thickening of the glomerular capillary walls. This may appear as a primary disorder or secondary to other diseases including infections and autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Various subtypes are classified by their abnormal ultrastructures and immune deposits. Hypocomplementemia is a characteristic feature of all types of MPGN.

**Tree numbers:** - C12.050.351.968.419.570.363.615 - C12.200.777.419.570.363.615 - C12.950.419.570.363.615 - C20.425

**Synonyms:** - Glomerulonephritis, Mesangiocapillary - Membranoproliferative Glomerulonephritis - Mesangiocapillary Glomerulonephritis - MPGN Membranoproliferative Glomerulonephritis - Glomerulonephritis, Hypocomplementemic