Leukemia, Myelogenous, Chronic, BCR-ABL Positive

**Definition:** Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.

**Tree numbers:** - C04.557.337.539.250 - C15.378.190.636.370 - C15.378.508.539.250 - C23.550.291.500.485

**Synonyms:** - Leukemia, Myelogenous, Chronic - Myelogenous Leukemia, Chronic - Leukemia, Myeloid, Philadelphia Positive - Myeloid Leukemia, Philadelphia-Positive - Leukemia, Myeloid, Philadelphia-Positive - Leukemia, Myelogenous, Ph1 Positive - Leukemia, Myelogenous, Ph1-Positive - Myelogenous Leukemia, Ph1-Positive - Leukemia, Myeloid, Ph1 Positive - Leukemia, Myeloid, Ph1-Positive - Myeloid Leukemia, Ph1-Positive - Leukemia, Chronic Myelogenous - Granulocytic Leukemia, Chronic - Leukemia, Granulocytic, Chronic - Myeloid Leukemia, Chronic - Leukemia, Myeloid, Chronic - Leukemia, Myelocytic, Chronic - Myelocytic Leukemia, Chronic - Leukemia, Chronic Myeloid