Inositol 1,4,5-Trisphosphate

**Definition:** Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.

**Tree numbers:** - D02.033.800.519.400.350 - D09.853.519.400.350 - D09.894.480.350

**Synonyms:** - 1,4,5-IP3 - Myo-Inositol 1,4,5-Trisphosphate - Myoinositol 1,4,5-Triphosphate - 1,4,5-InsP3 - Inositol 1,4,5-Triphosphate