Histiocytosis, Sinus

**Definition:** Benign, non-Langerhans-cell, histiocytic proliferative disorder that primarily affects the lymph nodes. It is often referred to as sinus histiocytosis with massive lymphadenopathy.

**Tree numbers:** - C15.604.250.410.450

**Synonyms:** - Destombes-Rosai-Dorfman Syndrome - Rosai-Dorfman Disease - Sinus Histiocytosis with Massive Lymphadenopathy