Gene Products, nef

**Definition:** Products of the retroviral NEF GENE. They play a role as accessory proteins that influence the rate of viral infectivity and the destruction of the host immune system. nef gene products were originally found as factors that trans-suppress viral replication and function as negative regulators of transcription. nef stands for negative factor.

**Tree numbers:** - D12.776.964.775.362 - D12.776.964.925.500

**Synonyms:** - 3'-orf Protein - Gene Product, nef - nef Gene Products - nef Protein