HIV Envelope Protein gp120

**Definition:** External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kDa and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV.

**Tree numbers:** - D12.776.964.350.520.350 - D12.776.964.775.325.164.249 - D12.776.964.775.562.500.500 - D12.776.964.970.880.325.164.249 - D23.050.327.520.350

**Synonyms:** - gp120(HIV) - Envelope Glycoprotein gp120, HIV - env Protein gp120, HIV - gp120 Envelope Glycoprotein, HIV - HIV Envelope Glycoprotein gp120 - HTLV-III gp120