Giant Cells, Foreign-Body

**Definition:** Multinucleated cells (fused macrophages), characteristic of granulomatous inflammation, which form around exogenous material in the skin. They are similar in appearance to Langhans giant cells (GIANT CELLS, LANGHANS), but foreign-body giant cells have more abundant chromatin and their nuclei are scattered in an irregular pattern in the cytoplasm.

**Tree numbers:** - A11.329.372.376 - A11.500.376 - A11.627.482.376 - A11.733.397.376 - A15.382.670.522.376 - A15.382.680.397.376

**Synonyms:** - Foreign Body-Type Giant Cells - Foreign Body Giant Cell - Foreign Body Giant Cells