2-Amino-5-phosphonovalerate

**Definition:** The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.

**Tree numbers:** - D12.125.070.950.100 - D12.125.740.025

**Synonyms:** - 2-APV - 5-Phosphononorvaline - 2-Amino-5-phosphonopentanoate - 2-Amino-5-phosphonopentanoic Acid - 2-Amino-5-phosphonovaleric Acid