Complement C3c

**Definition:** A 206-amino-acid fragment in the alpha chain (672-1663) of C3b. It is generated when C3b is inactivated (iC3b) and its alpha chain is cleaved by COMPLEMENT FACTOR I into C3c (749-954), and C3dg (955-1303) in the presence COMPLEMENT FACTOR H.

**Tree numbers:** - D12.776.124.486.274.250.260.500

**Synonyms:** - C3c Complement - Complement 3c - Complement C3c Fragment - Complement Component 3c