Macrophage Colony-Stimulating Factor

**Definition:** A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR).

**Tree numbers:** - D09.400.430.775.500 - D12.644.276.374.410.240.500 - D12.776.395.240.500 - D12.776.467.374.410.240.500 - D23.529.374.410.240.500

**Synonyms:** - Colony-Stimulating Factor 1 - CSF-1 - CSF-M - M-CSF - Colony-Stimulating Factor, Macrophage