Macrophage-Activating Factors

**Definition:** Factors secreted by stimulated lymphocytes that prime macrophages to become nonspecifically cytotoxic to tumors. They also modulate the expression of macrophage cell surface Ia antigens. One MAF is INTERFERON-GAMMA. Other factors antigenically distinct from IFN-gamma have also been identified.

**Tree numbers:** - D12.644.276.374.480.615 - D12.776.467.374.480.615 - D23.529.374.480.615