Kallikrein-Kinin System

**Definition:** A system of metabolic interactions by products produced in the distal nephron of the KIDNEY. These products include KALLIKREIN; KININS; KININASE I; KININASE II; and ENKEPHALINASE. This system participates in the control of renal functions. It interacts with the RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM to regulate BLOOD PRESSURE, generation of PROSTAGLANDINS, release of VASOPRESSINS, and WATER-ELECTROLYTE BALANCE.

**Tree numbers:** - G02.111.635.500.500 - G03.493.485 - G03.615.500.500 - G07.410.810.500.500 - G09.330.380.690